MIT Technology Review’s How To series helps you get things done.  Simon Willison has a plan for the end of the world. It’s a USB stick, onto which he has loaded a couple of his favorite open-weight LLMs—models that have been shared publicly by their creators and that can, in...

I’ll admit that I’ve rarely hesitated to point an accusing finger at air-conditioning. I’ve outlined in many stories and newsletters that AC is a significant contributor to global electricity demand, and it’s only going to suck up more power as temperatures rise. But I’ll also be the...

Eight babies have been born in the UK thanks to a technology that uses DNA from three people: the two biological parents plus a third person who supplies healthy mitochondrial DNA. The babies were born to mothers who carry genes for mitochondrial diseases and risked passing on severe...